anticoagulation agents
- Warfarin is a Vitamin K antagonist. Vitamin K is required for Factor 2, 7, 9, 10, C, S
- DOACS are direct oral anticoagulants. They are divided into 10a inhibitors and IIa inhibitors
- 10a inhibitors:
- Apixaban (Eliquis)
- Rivaroxaban (Xarelto)
- 2a inhibitors:
- dabigatran (Pradaxa)
- argatroban
Backlinks
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Coagulation Cascade
coagulation cascade
Coagulation
- Coagulation happens with
- endothelin release from site of damage leading to vasoconstriction
- endothelial damage leads to platelet activation leading to thrombus
- endothelial damage leads to coagulation factor activation. Fibrin is formed leading to thrombus
Cascade
Coagulation cascade has